Grey's Anatomy Season 22 Premieres With Major Explosion, Cast Returns

Grey's Anatomy returns for Season 22 on October 9, 2025, continuing from the explosive cliffhanger that endangered several characters, including Atticus “Link” Lincoln. Despite the explosion, Chris Carmack, who plays Link, is confirmed as a series regular, indicating his survival and ongoing story arc, especially as Jo is pregnant with their twins. Season 22 will feature returning fan favorites like Bailey, Webber, Owen, Teddy, and Jo, with Meredith Grey making appearances and continuing as the show's narrator. New additions include the show's first non-binary doctor, adding diversity and fresh storylines. Romance remains central, with particular focus on evolving relationships such as Jo's pregnancy journey and the anticipated progression of Amelia Shepherd and Monica Beltran's complex dynamic. The season promises a blend of medical drama, leadership challenges, and personal growth amid recovery from recent traumatic events at Grey Sloan Memorial.